Medical Inquiries and Observations is a four volume book internal medicine written by American physician and founder of Dickinson College, Dr. Benjamin Rush.

In the fourth volume, the reader will find a retraction of the author's former opinion of the yellow fever's spreading by contagion. He begs forgiveness of the friends of science and humanity, if the publication of that opinion has had any influence in increasing the misery and mortality attendant upon that disease. Indeed, such is the pain he feels, in recollecting that he ever entertained or propagated it, that it will long, and perhaps always, deprive him of the pleasure he might otherwise have derived from a review of his attempts to fulfill the public duties of his profession.

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